The Twelve Doctors is a fan created card game based on the enormously popular Dr. Who franchise.
From the Board Game Geek Description:
The Twelve Doctors is an unauthorised, non-profit and non-collectable card game set within the immensely popular Doctor Who universe.
Consisting of two balanced 60-card decks, the game pits two players against each other for the fate of the galaxy. One player takes the role of the Doctor in all his regenerations, and his opponent assumes control of his arch enemy, The Master.
The game has an asymmetrical design, with both decks featuring different cards and abilities. The Twelve Doctors is played using a 3-column time-line system, representing the battle for Gallifrey, Earth present and future, and Earth past. Gameplay is quick and bloodthirsty with companions EX-TER-MI-NATED! frequently, and marauders being dropped into black holes, or destroyed by the well-placed use of Venusian Aikido.