Constantinople is a print-and-play board game tracking the thousand year history of the Byzantine Empire. From the BGG description:
A Victory Point Games States of Siege Series style solitaire wargame covering the millennium-long history of the Byzantine empire, from the foundation of Constantinople in AD330 until its fall in AD1453. The player uses military might as well as diplomacy and outright bribery to keep the many opposing forces at bay for as long as possible. Can you outlive the historic Byzantine empire, or will your efforts be relegated to an obscure footnote in the history books?